drugset / Trial / NCT06046963

Sintilimab in Combination With S-1/Oxaliplatin With Nab-paclitaxel Intraperitoneal Infusion for Untreated Advanced Gastric Cancer With Malignant Ascites

NCT06046963 ↗

Phase 2 Unknown 35 enrolled Zhejiang Cancer Hospital
NaSingle-groupOpen-labelTreatment

Summary

To evaluate the efficacy and safety of Sintilimab in Combination With S-1/oxaliplatin With nab-paclitaxel intraperitoneal infusion as First-line Treatment for advanced gastric/gastroesophageal junction (GC/GEJ) adenocarcinoma with malignant ascites

Timeline

Start
2023-03-01
Primary completion
2024-03
Completion
2025-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Nab-paclitaxel Small molecule 100 mg/m2 Other
Subject Oxaliplatin Small molecule 130 mg/m2 Intravenous
Subject S-1 Small molecule — Oral
Subject Sintilimab Monoclonal antibody 200 mg Intravenous