Lithium Treatment to Prevent Cognitive Impairment After Brain Radiotherapy

Summary

Randomized, placebo-controlled, double-blinded, parallel group clinical trial to investigate if 6 months of oral lithium tablets (S-lithium 0,5-1,0 mmol/l) will prevent cognitive decline after brain radiotherapy in pediatric brain tumor survivors. Primary outcome measure is Processing Speed Index (PSI) 2 years after start of study treatment.

Timeline

Start

2024-02-16

Primary completion

2030-08-31

Completion

2033-08-31

Drugs

Indications