drugset / Trial / NCT06055712
Antibiotic Prophylaxis in Pediatric Open Fractures
RandomizedParallel-groupOpen-labelPrevention
Summary
This research will involve a prospective study on infection rates after grade 1 or 2 open fractures in the skeletally immature pediatric population. There will be 3 arms: one dose intravenous cefazolin, 24 hours intravenous cefazolin, and 24 hours intravenous cefazolin plus 5 days of oral cephalexin.
Timeline
- Start
- 2023-09-11
- Primary completion
- 2033-09
- Completion
- 2034-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | CEPHALEXIN ANHYDROUS | Small molecule | — | Oral |
| Comparator | Cefazolin | Small molecule | — | Intravenous |