drugset / Trial / NCT06060782
Thiotepa, Cyclophosphamide, Clarithromycin and Cytarabine
NaSingle-groupOpen-labelTreatment
Summary
This study is an observational study on the efficacy and safety of auto-HSCT in adult patients with Burkitt lymphoma, lymphoblastic lymphoma, and acute lymphoblastic leukemia who received TCCA conditioning regimen. The study plans to include 28 patients who received the TCCA regimen for pre-transplantation pretreatment before auto-HSCT. Maintenance treatment will be carried out after transplantation for 1 year to observe the efficacy and safety.
Timeline
- Start
- 2024-03-06
- Primary completion
- 2026-08-31
- Completion
- 2026-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Cladribine | Small molecule | 5 mg/m2 | — |
| Background | Cyclophosphamide | Other / unclassified | 40 mg/kg | — |
| Background | Cytarabine | Small molecule | 2 g | — |
| Background | Thiotepa | Other / unclassified | 5 mg/kg | — |