Search to Advance Limited Use of Opioids Pilot: Optimization of Non-Opioid Therapy With a Steroid

Summary

To provide health care professionals, including dentists, with the best possible evidence for clinical decision making when deciding upon analgesics and use of corticosteroid for acute post-surgical pain management; a pilot double blind randomized clinical trial will be conducted to test the hypothesis that use of preemptive dose of corticosteroid will reduce the need for opioid rescue. The impacted 3rd molar extraction model will be used due to the predictable severity of the post-operative pain and generalizability of results, as well as the fact that dentists write about one third of opioid prescriptions for adolescents.

Timeline

Start

2023-11-27

Primary completion

2024-09-30

Completion

2024-12-31

Outcome

Outcome not reported

Stopped (Business): “Terminated after 8 participants as prospect for funded is no longer viable”

Drugs

Indications

No indication recorded.