Intraarticular Steroids, Saline and Occupational Therapy in People With CMC1 Osteoarthritis

Phase 4 Recruiting 354 enrolled Diakonhjemmet Hospital Haugesund Rheumatism Hospital · collab Helse Stavanger HF · collab Nordlandssykehuset HF · collab St. Olavs Hospital · collab Vestre Viken Hospital Trust · collab

RandomizedParallel-groupTriple-blindTreatment

Summary

A placebo-controlled randomized controlled trial exploring the effect of intraarticular steroids, saline or an occupational therapy intervention in inflammatory carpometacarpal-1 osteoarthritis

Timeline

Start: 2023-11-03
Primary completion: 2027-01
Completion: 2028-10

Publications

Gloersen M, Kjeken I, Tveter AT, Kazemi A, Sexton J, Dziedzic K, Felson DT, Stamm TA, Guermazi A, Hermann-Eriksen M, Saether MI, Lundby K, Espero EL, Olsen M, Norheim KB, Fister EB, Hoff M, Uleberg JK, Midtgard IP, Andreassen T, Sjolie D, Sletten H, Hammer HB, Haugen IK; PICASSO study team. Study protocol for the PICASSO trial: A randomized placebo-controlled trial to investigate the efficacy and safety of intraarticular steroid injections and an occupational therapy intervention in painful inflammatory carpometacarpal-1 osteoarthritis. Osteoarthr Cartil Open. 2024 Nov 19;7(1):100542. doi: 10.1016/j.ocarto.2024.100542. eCollection 2025 Mar.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Triamcinolone Acetonide	Other / unclassified	0.5 ml	Other
Subject	Triamcinolone Acetonide	Other / unclassified	40 mg/ml	Other

Intraarticular Steroids, Saline and Occupational Therapy in People With CMC1 Osteoarthritis

Summary

Timeline

Publications

Drugs

Indications