drugset / Trial / NCT06090565
Cefixime Plus Doxycycline Compared to Ceftriaxone Plus Azithromycin for Treatment of Gonorrhoea
RandomizedParallel-groupSingle-blindTreatment
Summary
A non-inferiority, open-label, multicentre randomised controlled trial to compare two therapeutic regimens for the treatment of uncomplicated urogenital, rectal or pharyngeal gonorrhoea in men and women between 18 and 75 years of age. Patients were enrolled and treated from April 2021 to June 2022 at the Dermatovenerology Department, University Hospital Bulovka, Prague, Czech Republic and the Venereology Prague, Medicentrum Beroun, Prague, Czech Republic.
Timeline
- Start
- 2021-04-01
- Primary completion
- 2022-06-30
- Completion
- 2022-12-22
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Azithromycin | Small molecule | 2 g | Oral |
| Subject | Cefixime | Other / unclassified | 800 mg | Oral |
| Comparator | Ceftriaxone | Other / unclassified | 1 g | Intramuscular |
| Subject | Doxycycline | Small molecule | 100 mg | Oral |