drugset / Trial / NCT06115642

A Phase I Study to Evaluate the Safety, Tolerability, and PK of HLX43 in Advanced/Metastatic Solid Tumors

NCT06115642

Phase 1 Enrolling by invitation 367 enrolled Shanghai Henlius Biotech
RandomizedParallel-groupOpen-labelTreatment

Summary

This study is an open-label first-in-human phase I clinical study to evaluate the safety, tolerability, and pharmacokinetic characteristics of HLX43 in patients with advanced/metastatic solid tumors.

Timeline

Start
2023-11-24
Primary completion
2026-06-30
Completion
2027-11-30

Drugs

EvaluationDrugModalityDoseRoute
Subject HLX43 Other / unclassified Intravenous
Background Serplulimab Monoclonal antibody 300 mg Intravenous