drugset / Trial / NCT06121843

A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of Arlocabtagene Autoleucel (BMS-986393) in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma

NCT06121843

Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to establish a safe and tolerable dose of arlocabtagene autoleucel (BMS-986393) in combinations with alnuctamab, mezigdomide, iberdomide, and elranatamab in participants with relapsed and/or refractory multiple myeloma (RRMM).

Timeline

Start
2024-02-22
Primary completion
2028-08-01
Completion
2028-08-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Alnuctamab Protein / enzyme biologic
Subject Arlocabtagene Autoleucel Unknown
Subject Elranatamab Monoclonal antibody
Subject Iberdomide Small molecule
Subject Mezigdomide Small molecule
Background Dexamethasone Small molecule

Indications