drugset
drugset / Trial / NCT06140758

Evaluation of the Anticaries Efficacy of Dentifrice Formulations Using an In-situ Model

NCT06140758 ↗

Completed 12 enrolled Procter and Gamble
RandomizedCrossoverTriple-blindTreatment

Summary

The primary objective is to compare the remineralization and demineralization inhibition potential of early subsurface carious lesions in enamel in situ after rinsing with six different aqueous slurries of toothpaste formulations.

Timeline

Start
2023-07-31
Primary completion
2023-12-11
Completion
2023-12-11

Drugs

EvaluationDrugModalityDoseRoute
Comparator sodium monofluorophosphate Unknown 1.1 % Other
Comparator sodium monofluorophosphate Unknown 1.16 % Other
Comparator sodium monofluorophosphate Unknown 1450 ppm Other
Comparator sodium monofluorophosphate Unknown 1500 ppm Other
Comparator stannous fluoride Small molecule 0.454 % Other
Comparator stannous fluoride Small molecule 1100 ppm Other

Indications

dental caries