drugset / Trial / NCT06141226

Phase II Clinical Trial to Evaluate the Safety and Efficacy of TQB2450 Injection Combined With Anlotinib Capsule and Chemotherapy in the Treatment of Immunoresistant Advanced Non-small Cell Lung Cancer

NCT06141226

RandomizedParallel-groupQuadruple-blindTreatment

Summary

Objective to compare the efficacy and safety of TQB2450 injection combined with anlotinib and chemotherapy, and TQB2450 injection combined with chemotherapy in the treatment of advanced non-small cell lung cancer subjects who failed to receive first-line chemotherapy combined with immunization, and to explore and evaluate biomarkers related to efficacy, mechanism of action / resistance mechanism, and safety.

Timeline

Start
2023-04-12
Primary completion
2027-12-30
Completion
2028-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Catequentinib Small molecule Oral
Background Benmelstobart Monoclonal antibody 1200 mg Intravenous
Background Docetaxel Small molecule 60 mg/m2 Intravenous