drugset / Trial / NCT06150703

Luteal Phase Support With GnRH Agonist After GnRH Agonist Triggering in IVF/ICSI Cycles

NCT06150703

Phase 3 Recruiting 652 enrolled Assistance Publique - Hôpitaux de Paris
RandomizedParallel-groupOpen-labelTreatment

Summary

The development of stimulation protocols for in vitro fertilisation (IVF) has led to a paradox. It has now been established that obtaining a large number of oocytes is a key to success, but that it is also a risk factor for embryo transfer failure after puncture (disruption of endometrial receptivity due to luteal insufficiency) and a risk factor for complications such as ovarian hyperstimulation syndrome (OHSS).

Timeline

Start
2024-06-27
Primary completion
2027-09
Completion
2027-09-27

Drugs

EvaluationDrugModalityDoseRoute
Subject Nafarelin Other / unclassified 200 ug Intranasal
Comparator Progesterone Other / unclassified 200 mg Intravenous
Subject Triptorelin Other / unclassified 0.2 mg Subcutaneous
Comparator hCG Unknown 250 ug Subcutaneous

Indications

No indication recorded.