drugset / Trial / NCT06176339

Assessing the Clinical Utility of Adding Pentoxifylline to Neoadjuvant Chemotherapy Protocols in Breast Cancer Patients"

NCT06176339

Phase 2 Unknown 70 enrolled Mansoura University
RandomizedParallel-groupDouble-blindTreatment

Summary

Breast cancer, a leading cause of cancer-related mortality in women worldwide, has spurred the investigation of novel therapeutic approaches. Pentoxifylline (PTX), a synthetic methylxanthine derivative, has shown promise in preclinical studies when combined with conventional anticancer drugs. This study aims to assess PTX's impact when added to neoadjuvant chemotherapy protocols in breast cancer patients, with the goal of improving treatment outcomes and reducing associated toxicities.

Timeline

Start
2023-12-15
Primary completion
2024-08-30
Completion
2024-09-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Pentoxifylline Small molecule 400 mg Oral