drugset / Trial / NCT06188052

Efficacy of Topical Versus Intravenous Tranexamic Acid in Controlling Blood Loss

NCT06188052

Phase 4 Unknown 45 enrolled Kasr El Aini Hospital
RandomizedParallel-groupDouble-blindTreatment

Summary

Total laryngectomy with bilateral block neck dissection is considered one of the major head and neck surgeries. Intraoperative bleeding is considered a risk factor for this operation specially that the population of this operation are elder with multiple comorbidities. Intravenous administration of tranexamic acid reduces bleeding during surgery.We design this study aiming to prove the role of topical tranexamic acid in controlling the intraoperative bleeding in patients undergoing total laryngectomy operation avoiding the risk of intravenous administration.

Timeline

Start
2023-08-01
Primary completion
2024-01-10
Completion
2024-01-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Tranexamic Acid Small molecule 1 mg/kg Intravenous
Comparator Tranexamic Acid Small molecule 2 mg/kg Intravenous

Indications

No indication recorded.