Neurocognitive Mechanisms of Perimenstrual Estrogen Effects on Suicidality

Summary

This within-person, crossover, 2-condition, placebo-controlled study compares the impact of two perimenstrual conditions on severity of suicidal symptoms in females with past-month suicidality but minimal risk of imminent suicide attempt. The two conditions are (1) perimenstrual administration of estradiol and (2) natural perimenstrual withdrawal from estradiol during placebo.

Timeline

Start

2024-03-16

Primary completion

2024-12-01

Completion

2024-12-01

Drugs

Indications

No indication recorded.