drugset / Trial / NCT06193811
A Study in Healthy People to Compare Two Different Tablets of BI 685509 and to Test How Food and Esomeprazole Influence the Amount of BI 685509 in the Blood
RandomizedCrossoverOpen-labelTreatment
Summary
The main objective of this trial is to investigate: * the relative bioavailability of Avenciguat (BI 685509) TF2 (Reference, R) vs. Avenciguat (BI 685509) iCF (Test 1, T1) tablets under fasted conditions * the relative bioavailability of Avenciguat (BI 685509) iCF tablets under fasted (T1) and fed (Test 2, T2) conditions * the relative bioavailability of Avenciguat (BI 685509) iCF tablets given alone (T1) and together with esomeprazole (Test 3, T3) under fasted conditions
Timeline
- Start
- 2024-01-16
- Primary completion
- 2024-03-14
- Completion
- 2024-03-14
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Avenciguat | Small molecule | — | Oral |
| Subject | Esomeprazole | Small molecule | — | Oral |
Indications
No indication recorded.