drugset / Trial / NCT06195189

Sunvozertinib Combined With Chemotherapy for EGFRm After EGFR-TKI Treatment Failure:Phase I/II

NCT06195189

Phase 1/2 Recruiting 40 enrolled Sichuan University
NaSingle-groupOpen-labelTreatment

Summary

To access the anti-tumor efficacy, safety and tolerability of Sunvozertinib combined with chemotherapy in patients with locally advanced or metastatic non-small-cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) sensitizing mutations who have progressed following standard TKI therapy.

Timeline

Start
2024-02-29
Primary completion
2027-12-30
Completion
2028-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Sunvozertinib Small molecule 200 mg
Background Pemetrexed Small molecule