drugset / Trial / NCT06200168

Electroacupuncture for the Prevention of Chemotherapy-induced Nausea and Vomiting in Patients With Breast Cancer

NCT06200168

Phase 3 Recruiting 370 enrolled Jiuda Zhao
RandomizedParallel-groupTriple-blindTreatment

Summary

This randomized controlled phase III trial aims to evaluate the use of electroacupuncture in combination with olanzapine-containing standard quadruple antiemetic drugs for the treatment of nausea and vomiting induced by highly emetogenic chemotherapy (HEC) in patients with breast cancer. Furthermore, it will analyze the relationship between single nucleotide polymorphism and electroacupuncture treatment for chemotherapy-induced nausea and vomiting.

Timeline

Start
2024-01-16
Primary completion
2026-10-31
Completion
2026-12-31

Drugs

EvaluationDrugModalityDoseRoute
Background Aprepitant Other / unclassified 130 mg Intravenous
Background Fosaprepitant Other / unclassified 150 mg Intravenous
Background Olanzapine Small molecule 2.5 mg Oral
Background Palonosetron Other / unclassified 0.25 mg Intravenous

Indications

No indication recorded.