drugset / Trial / NCT06206733
ASKB589 in Combination With CAPOX and PD-1 Inhibitor in Patients With Advanced or Metastatic GC/GEJ Adenocarcinoma
Phase 3
Active not recruiting
780 enrolled
AskGene Pharma, Inc.
Jiangsu Aosaikang Pharmaceutical Co., Ltd. · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This study is a multicenter, randomized, double-blind, standard-of-care controlled phase III clinical study conducted in China. The purpose of this study is to evaluate the efficacy of ASKB589 plus CAPOX and PD-1 inhibitor compared with placebo plus CAPOX and PD-1 inhibitor (as first-line treatment) as measured by Progression Free Survival (PFS).
Timeline
- Start
- 2024-01-25
- Primary completion
- 2026-12-30
- Completion
- 2028-12-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | ASKB589 | Unknown | — | Intravenous |
| Background | Capecitabine | Small molecule | — | Oral |
| Background | Oxaliplatin | Small molecule | — | Intravenous |
| Background | Tislelizumab | Monoclonal antibody | — | Intravenous |