NCT06208956: A Low Dose Dexmedetomidine in Sedation Colonoscopy

Summary

104 patients who undergo painless colonoscopy from January 20,2024 to February 29,2024 will be randomized to two groups: propofol group and dexmedetomidine group. In the dexmedetomidine group,dexmedetomidine is infusion intravenously with a loading dose of 0.5 μg kg-1 for 10 min, then infusion at 0.3 μg kg-1 h-1 according to the ideal body weight of the patient until the end of colonoscopy. In the propofol group, Propofol is administrated 1 mg kg-1 intravenously, then titrated given by 0.5 mg kg-1 during the whole process.

Timeline

Start: 2024-01-20
Primary completion: 2024-02-29
Completion: 2024-02-29

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Dexmedetomidine	Other / unclassified	0.3 ug/kg	Intravenous
Subject	Propofol	Small molecule	0.5 mg/kg	Intravenous

Indications

No indication recorded.