drugset / Trial / NCT06210594
Staph Intervention for Effective Local Defense
Phase 4
Completed
78 enrolled
Johns Hopkins Bloomberg School of Public Health
National Institute of General Medical Sciences (NIGMS) · collab
RandomizedParallel-groupOpen-labelPrevention
Summary
Indigenous persons experience a high burden of Staphylococcus aureus (SA) invasive disease and skin and soft tissue infections. SA carriage on the skin is factor for development of SA infections. The goal of this clinical trial is to evaluate a community-informed approach to reduce carriage of SA. Participants will be assigned to education and household supplies for prevention of SA with and without a biomedical intervention. Researchers will compare SA carriage in the two groups.
Timeline
- Start
- 2024-04-01
- Primary completion
- 2025-11-14
- Completion
- 2025-11-14
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Chlorhexidine gluconate | Other / unclassified | — | Topical |
| Subject | Mupirocin | Small molecule | — | Intranasal |
| Subject | Nozin | Unknown | — | Intranasal |