drugset / Trial / NCT06223711

Durvalumab With Consolidative Radiochemotherapy and Ablative Stereotactic Radiotherapy in Oligometastatic ES-SCLC

NCT06223711 ↗

Phase 2 Recruiting 43 enrolled Saarland University
NaSingle-groupOpen-labelTreatment

Summary

Open-label, single-arm, prospective multicenter phase II clinical trial to determine the efficacy of immunotherapy with durvalumab concomitant with radiochemotherapy, followed by durvalumab maintenance therapy in combination with stereotactic radiotherapy in extensive stage SCLC

Timeline

Start
2023-10-06
Primary completion
2027-03
Completion
2027-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Durvalumab Monoclonal antibody 1500 mg —
Background Carboplatin Small molecule 5 unknown —
Background Cisplatin Other / unclassified 75 mg/m2 —
Background Etoposide Small molecule 90 mg/m2 —