Comparative Pharmacokinetic Study of Aprepitant Injection in Humans

Summary

This is a single-center, open, randomized, single-dose, two-cycle, two-sequence, crossover pharmacokinetic study in healthy adult subjects. The trial is planned to enroll 24 healthy subjects. Subjects will be randomized to one of two groups (Group A: T-R, Group B: R-T) according to the randomization table. The washout period (dosing interval) between doses will be at least 7 days. For example, for a washout period of 7 days, all subjects will receive the appropriate drug according to the randomized schedule on Day 1 of Cycle 1 and Day 8 of Cycle 2 of the trial.

Timeline

Start

2024-01-23

Primary completion

2024-01-25

Completion

2025-01-25

Drugs

Indications

No indication recorded.