Effect of Silymarin Against Methotrexate-induced Liver Injury in Rheumatic Diseases

Unknown 72 enrolled Phramongkutklao College of Medicine and Hospital

RandomizedParallel-groupDouble-blindTreatment

Summary

To study the effect of silymarin against methotrexate-induced liver injury in rheumatic diseases including rheumatoid arthritis, psoriatric arthritis and psoriasis

Timeline

Start: 2024-02-01
Primary completion: 2025-04
Completion: 2025-04

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Silymarin	Traditional medicine (herbal / TCM)	140 mg	Oral

Effect of Silymarin Against Methotrexate-induced Liver Injury in Rheumatic Diseases

Summary

Timeline

Drugs

Indications