drugset / Trial / NCT06278038
Efficacy and Safety of Toludesvenlafaxine Hydrochloride Sustained-release Tablets Versus Venlafaxine Hydrochloride Sustained-release Tablets in Patients With Major Depression Disorder
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to evaluate efficacy and safety of toludesvenlafaxine hydrochloride sustained-release tablets in the treatment of major depression disorder compared to venlafaxine hydrochloride sustained-release tablets, to provide evidence-based basis for clinical rational drug use.
Timeline
- Start
- 2024-02-22
- Primary completion
- 2024-11-10
- Completion
- 2024-11-19
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Toludesvenlafaxine | Small molecule | 80 mg | Oral |
| Subject | Toludesvenlafaxine | Small molecule | 120 mg | Oral |
| Subject | Toludesvenlafaxine | Small molecule | 160 mg | Oral |
| Comparator | Venlafaxine | Small molecule | 75 mg | Oral |
| Comparator | Venlafaxine | Small molecule | 150 mg | Oral |
| Comparator | Venlafaxine | Small molecule | 225 mg | Oral |