Drugs / Toludesvenlafaxine

Trials 17 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 17 trials
Phase 1 NCT03822065 Jan → Feb 2019 major depressive disorder Luye Pharma Group Ltd. Completed No outcome recorded
Phase 1 NCT03733574 Jun → Jul 2018 major depressive disorder Luye Pharma Group Ltd. Completed No outcome recorded
Phase 1 NCT03357796 Nov → Dec 2017 major depressive disorder Luye Pharma Group Ltd. Completed No outcome recorded
Phase 1 NCT02988024 Dec 2016 major depressive disorder Luye Pharma Group Ltd. Completed No outcome recorded
Phase 1 NCT03785652 Oct 2015 major depressive disorder Luye Pharma Group Ltd. Completed No outcome recorded
Phase 1 NCT02271412 Oct 2014 → Mar 2015 major depressive disorder Luye Pharma Group Ltd. Completed No outcome recorded
Phase 1 NCT02055300 Feb → Aug 2014 major depressive disorder Luye Pharma Group Ltd. Completed No outcome recorded
Phase 32 trials
Phase 3 NCT05970510 Aug 2023 → Jul 2025 generalized anxiety disorder Luye Pharma Group Ltd. Completed No outcome recorded
Phase 3 NCT04853407 Dec 2018 → Dec 2020 major depressive disorder Luye Pharma Group Ltd. Completed No outcome recorded
Phase 44 trials
Phase 4 NCT07552246 Apr 2026 → Mar 2027 expected mixed anxiety and depressive disorder Duke Kunshan University Not yet recruiting No outcome recorded
Phase 4 NCT06426485 May 2024 → Feb 2027 expected major depressive disorder Luye Pharma Group Ltd. Not yet recruiting No outcome recorded
Phase 4 NCT06026917 Sep 2023 → Jan 2024 major depressive disorder Shanghai Mental Health Center Unknown No outcome recorded
Phase 4 NCT05849272 May 2023 → May 2024 somatoform disorder Shanghai Mental Health Center Completed No outcome recorded
Phase not applicable4 trials
NCT07709416 Sep 2026 → Sep 2028 expected Beijing Tiantan Hospital Not yet recruiting No outcome recorded
NCT07208357 Oct 2025 → Jun 2027 expected fibromyalgia Beijing Tiantan Hospital Recruiting No outcome recorded
NCT06278038 Feb → Nov 2024 major depressive disorder First Affiliated Hospital of Zhejiang University Completed No outcome recorded
NCT06270433 Feb → Dec 2024 atypical depressive disorder Jiangsu Province Nanjing Brain Hospital Unknown No outcome recorded

Evidence & citations 14 cited values

Every value below carries the sentence it was read from. 19 sources stand behind the page.

FieldValueCited text
Known as Toludesvenlafaxine “Administer Toludesvenlafaxine (40-80 mg daily) or imported Sertraline (50-200 mg daily), supplemented with Lorazepam (0.4-0.8 mg) or Alprazolam (0.4-0.8 mg) as needed for sleep support.” NCT07552246
8

NCT06270433

NCT06026917

NCT07709416

NCT06278038

NCT05970510

NCT06426485

NCT05849272

NCT07208357

Known as ansofaxine “A phase 3, multicenter, double-blind, randomized, placebo-controlled clinical trial to verify the efficacy and safety of ansofaxine (LY03005) for major depressive disorder.” PMID 37164957 May 2023
Known as LPM-570065 ChEMBL registry synonym — accepted as the source's own label CHEMBL4227736
Known as LPM-570065 FREE BASE ChEMBL registry synonym — accepted as the source's own label CHEMBL4227736
Known as LY-03005 HYDROCHLORIDE DIHYDRATE ChEMBL registry synonym — accepted as the source's own label CHEMBL4227736
Known as LY03005 “A phase 3, multicenter, double-blind, randomized, placebo-controlled clinical trial to verify the efficacy and safety of ansofaxine (LY03005) for major depressive disorder.” PMID 37164957 May 2023
7

NCT03733574

NCT03785652

NCT03357796

NCT02988024

NCT03822065

NCT02055300

NCT02271412

Known as ODVP2 ChEMBL registry synonym — accepted as the source's own label CHEMBL4227736
Known as ODVP2 HYDROCHLORIDE DIHYDRATE ChEMBL registry synonym — accepted as the source's own label CHEMBL4227736
Known as Roxylin “OBJECTIVE: This study aimed to evaluate the efficacy and safety of toludesvenlafaxine hydrochloride sustained-release tablets (Roxylin®) for somatic symptoms of major...” PMID 40661857 Jul 2025
Known as Toludesvenlafaxina ChEMBL registry synonym — accepted as the source's own label CHEMBL4227736
Known as Toludesvenlafaxine hydrochloride Toludesvenlafaxine hydrochloride sustained-release tablets” NCT06270433
1

Toludesvenlafaxine Hydrochloride Sustained-release Tablets” NCT06426485

Action Inhibit “a potential triple reuptake inhibitor of serotonin, norepinephrine, and dopamine” PMID 37164957 May 2023
Modality Small molecule CHEMBL4227736
Route Oral “single oral doses of LY03005” NCT02055300