drugset / Trial / NCT06285097

A Study of PF-07820435 as a Single Agent and in Combination in Participants With Advanced Solid Tumors

NCT06285097

Phase 1 Terminated 9 enrolled Pfizer
Non-randomizedSequentialOpen-labelTreatment

Summary

This study aims to evaluate the safety, and early signals of anti-tumor activity of PF-07820435 when administered alone (Part 1A) or in combination with sasanlimab (Part 1B; Part 2) in patients with selected advanced or metastatic solid tumors. Part 1 will be dose-finding and Part 2 of the study will further evaluate PF-07820435 at the recommended dose for combination expansion in patients with selected advanced solid tumors.

Timeline

Start
2024-02-08
Primary completion
2025-01-03
Completion
2025-02-13

Drugs

EvaluationDrugModalityDoseRoute
Subject PF-07820435 Unknown Oral
Subject Sasanlimab Monoclonal antibody Subcutaneous