drugset / Trial / NCT06285097
A Study of PF-07820435 as a Single Agent and in Combination in Participants With Advanced Solid Tumors
Non-randomizedSequentialOpen-labelTreatment
Summary
This study aims to evaluate the safety, and early signals of anti-tumor activity of PF-07820435 when administered alone (Part 1A) or in combination with sasanlimab (Part 1B; Part 2) in patients with selected advanced or metastatic solid tumors. Part 1 will be dose-finding and Part 2 of the study will further evaluate PF-07820435 at the recommended dose for combination expansion in patients with selected advanced solid tumors.
Timeline
- Start
- 2024-02-08
- Primary completion
- 2025-01-03
- Completion
- 2025-02-13
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | PF-07820435 | Unknown | — | Oral |
| Subject | Sasanlimab | Monoclonal antibody | — | Subcutaneous |