Drugs / Sasanlimab

Trials 25 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 118 trials
Phase 1 NCT07206225 Nov 2025 → Jan 2030 expected non-invasive bladder urothelial carcinoma Pfizer Recruiting No outcome recorded
Phase 1 NCT06870487 May 2025 → Apr 2026 classic Hodgkin lymphoma, diffuse large B-cell lymphoma, head and neck squamous cell carcinoma, melanoma +2 Pfizer Terminated No outcome recorded
Phase 1 NCT06974734 May 2025 → Mar 2026 head and neck squamous cell carcinoma, melanoma, non-small cell lung carcinoma, pancreatic ductal adenocarcinoma Pfizer Terminated No outcome recorded
Phase 1 NCT06704724 Dec 2024 → May 2026 colorectal neoplasm, non-small cell lung carcinoma, pancreatic ductal adenocarcinoma Pfizer Terminated No outcome recorded
Phase 1 NCT06580938 Nov 2024 → Jul 2025 colorectal cancer, head and neck cancer, melanoma, non-small cell lung carcinoma +2 Pfizer Terminated No outcome recorded
Phase 1 NCT06546553 Sep 2024 → Oct 2025 colorectal carcinoma, head and neck squamous cell carcinoma, non-small cell lung carcinoma, ovarian carcinoma +1 Pfizer Terminated No outcome recorded
Phase 1 NCT06447662 Jun 2024 → Oct 2026 expected colorectal neoplasm, non-small cell lung carcinoma, pancreatic ductal adenocarcinoma Pfizer Active not recruiting No outcome recorded
Phase 1 NCT06448364 May → Aug 2024 colorectal cancer, melanoma, non-small cell lung carcinoma, urothelial carcinoma Pfizer Terminated No outcome recorded
Phase 1 NCT06285097 Feb 2024 → Jan 2025 colorectal carcinoma, head and neck squamous cell carcinoma, melanoma, non-small cell lung carcinoma +3 Pfizer Terminated No outcome recorded
Phase 1 NCT05259397 Mar → Sep 2022 urinary bladder cancer Pfizer Withdrawn No outcome recorded
Phase 1/23 trials
Phase 1/2 NCT05665361 Apr 2024 → Jun 2027 expected clear cell renal carcinoma, papillary renal cell carcinoma National Cancer Institute (NCI) Recruiting No outcome recorded
Phase 1/2 NCT04585815 Nov 2020 → May 2023 non-small cell lung carcinoma Pfizer Terminated No outcome recorded
Phase 1/2 NCT04181788 Mar 2020 → Mar 2022 non-small cell lung carcinoma Pfizer Completed No outcome recorded
Phase 23 trials
Phase 2 NCT07123090 Nov 2025 → Oct 2026 expected clear cell renal carcinoma Stephanie Berg Recruiting No outcome recorded
Phase 2 NCT06089265 Jun → Nov 2023 hereditary fructose intolerance Maastricht University Medical Center Completed No outcome recorded
Phase 2 NCT05241340 Feb 2022 → Aug 2025 overdue infiltrating bladder urothelial carcinoma The Methodist Hospital Research Institute Active not recruiting No outcome recorded
Phase 31 trial
Phase 3 NCT04165317 Dec 2019 → Dec 2024 overdue urinary bladder carcinoma Pfizer Active not recruiting No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2/3 NCT06218069 Comparator Feb → Dec 2025 overdue non-small cell lung carcinoma Radboud University Medical Center Not yet recruiting No outcome recorded

Press releases naming this drug 2 releases

DateIssuerRelease
2025-04-26 Pfizer Pfizer’s Sasanlimab Combination Significantly Improves Event-Free Survival in BCG-Naïve, High-Risk Non-Muscle Invasive Bladder Cancer pfizer.com
2025-01-10 Pfizer Pfizer’s Sasanlimab in Combination with BCG Improves Event-Free Survival in Patients with BCG-Naïve, High-Risk Non-Muscle Invasive Bladder Cancer pfizer.com

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 29 sources stand behind the page.

FieldValueCited text
Known as Sasanlimab ClinicalTrials.gov intervention name — accepted as the source's own label NCT07206225
18

NCT05061537

NCT05665361

NCT06285097

NCT06218069

NCT06546553

NCT05259397

NCT06704724

NCT04585815

NCT06448364

NCT06580938

NCT05233436

NCT06974734

NCT05241340

NCT07123090

NCT04254107

NCT06870487

NCT06447662

NCT04458259

Known as PF-06801591 “Anti-PD1 PF-06801591NCT04171141
6

NCT04181788

NCT06089265

NCT04152018

NCT04165317

NCT02616185

NCT02573259

Known as RN-888 ChEMBL registry synonym — accepted as the source's own label CHEMBL4298191
Action Inhibit “blocks its interaction with PD-1 ligands” PMID 31145415 Jul 2019
Modality Monoclonal antibody “a humanized immunoglobulin G4 monoclonal antibodyPMID 31145415 Jul 2019
Route Subcutaneous subcutaneously at 300 mg every 4 weeks” PMID 34694529 Oct 2021
Target PDCD1 “A monoclonal antibody (mAb) that blocks the interaction between PD-1 and PDL1/ PD-L2.” NCT04181788