drugset / Trial / NCT07123090

A Study of Sasanlimab, Palbociclib and Axitinib in Metastatic Renal Cell Carcinoma

NCT07123090

Phase 2 Recruiting 25 enrolled Stephanie Berg Pfizer · collab
NaSingle-groupOpen-labelTreatment

Summary

The goal of this research study is to evaluate how well and safely the study drugs sasanlimab, palbociclib, and axitinib work for treatment of participants with advanced clear cell renal cell carcinoma (ccRCC) or translocation renal cell carcinoma (tRCC). The name of the study drugs involved in this research study is: * Sasanlimab (a type of monoclonal antibody) * Palbociclib (a type of kinase inhibitor) * Axitinib (a type of Vascular endothelial growth factor inhibitor)

Timeline

Start
2025-11-24
Primary completion
2026-10-01
Completion
2028-02-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Axitinib Small molecule Oral
Subject Palbociclib Small molecule Oral
Subject Sasanlimab Monoclonal antibody Subcutaneous