Molecular Analysis of Intracanal Microbes After Chemomechanical Procedure and Root Canal Medication: A Randomized Controlled Trial

Summary

This study aimed to evaluate clinically the intracanal microbes at molecular level after using established root canal medicament Calcium hydroxide and potential root canal medicament Glycyrrhizin.and Decontamination Analysis of Controls samples.

Timeline

Start

2022-05-03

Primary completion

2023-12-20

Completion

2024-01-15

Publications

• Khaleefah OT, El-Baz AM, Gomaa MA, Badr AE. Molecular analysis of intracanal microbial reduction to compare the effectiveness of glycyrrhizin and calcium hydroxide as intracanal medications: a randomised controlled trial. BMC Oral Health. 2026 Mar 11;26(1):731. doi: 10.1186/s12903-026-07906-6.

Drugs

Indications