drugset / Trial / NCT06291727
Mepivacaine vs Bupivacaine Spinal Anesthesia for TKA
RandomizedParallel-groupDouble-blindTreatment
Summary
This study is a prospective, double-blind prospective randomized controlled trial comparing mepivacaine and bupivacaine spinal anesthesia for same-day discharge readiness following a unilateral primary elective TKA procedure. Study data will be collected during the patient's hospital stay for their TKA procedure, and the primary outcome of same-day discharge readiness will be assessed the day of surgery. Patients will also be contacted at Day 3 post-op to assess for any complications, current level of pain, and pain medication utilization.
Timeline
- Start
- 2024-02-16
- Primary completion
- 2025-08-01
- Completion
- 2025-08-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Bupivacaine | Other / unclassified | 10.5 mg | Other |
| Comparator | Mepivacaine | Other / unclassified | 67.5 mg | — |