drugset / Trial / NCT06291727

Mepivacaine vs Bupivacaine Spinal Anesthesia for TKA

NCT06291727

Phase 4 Completed 138 enrolled Prisma Health-Upstate
RandomizedParallel-groupDouble-blindTreatment

Summary

This study is a prospective, double-blind prospective randomized controlled trial comparing mepivacaine and bupivacaine spinal anesthesia for same-day discharge readiness following a unilateral primary elective TKA procedure. Study data will be collected during the patient's hospital stay for their TKA procedure, and the primary outcome of same-day discharge readiness will be assessed the day of surgery. Patients will also be contacted at Day 3 post-op to assess for any complications, current level of pain, and pain medication utilization.

Timeline

Start
2024-02-16
Primary completion
2025-08-01
Completion
2025-08-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Bupivacaine Other / unclassified 10.5 mg Other
Comparator Mepivacaine Other / unclassified 67.5 mg

Indications