drugset / Trial / NCT06292091
A Study to Investigate the Effect of Urine Acid-base Disequilibrium on the Pharmacokinetics of Captopril
Non-randomizedSequentialOpen-labelOther
Summary
The aim of this study is to evaluate the effect of urine acid-base disequilibrium on the pharmacokinetics of captopril in healthy male volunteers.
Timeline
- Start
- 2024-02-28
- Primary completion
- 2024-03-27
- Completion
- 2024-04-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Captopril | Small molecule | 12.5 mg | — |
| Subject | Torsemide | Other / unclassified | 20 mg | — |
| Subject | sodium bicarbonate | Diagnostic / imaging agent | 4 g | — |