Effect of Vitamin D Injection on Hypertrophic Scars and Keloids

Summary

Scars and keloids cause patients severe morbidity and psychological distress. Hypertrophic scars rise above the skin but stay within the scar boundaries, while keloids expand. The development of keloids and hypertrophic scars is a consequence of insufficient wound healing. These lesions are distinguished by excessive ECM deposition. Excessive ECM deposition is caused by increased inflammatory and proliferative processes and decreased remodeling activities. These scarring lesions are also linked to genetic and systemic causes

Timeline

Start

2024-02-27

Primary completion

2025-02-20

Completion

2025-02-20

Publications

• Hassan AR, Binsaleh AY, El-Tahlawi SM, El-Amir AM, Ishak MM, Alsubaie N, El-Masry TA, Bahaa MM, Eldesoqui M, Kamal M. Impact of Vitamin D Injection on Keloids and Hypertrophic Scars. J Cosmet Dermatol. 2025 Apr;24(4):e70118. doi: 10.1111/jocd.70118.

Drugs

Indications