drugset / Trial / NCT06301880

Effect of Topically-applied Milrinone or Nitroglycerin on Internal Mammary Artery Free Flow

NCT06301880

Phase 3 Completed 46 enrolled Damascus University
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Forty-six consecutive patients undergoing elective primary coronary artery bypass grafting were enrolled. After the left IMA was harvested, free flow was measured under controlled hemodynamic conditions before any intervention (flow 1) and at a mean of 12.5 minutes after the topical application of one of three agents (milrinone, nitroglycerin or normal saline) on the IMA (flow 2).

Timeline

Start
2022-01-01
Primary completion
2023-01-31
Completion
2023-01-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Milrinone Small molecule 10 mg Topical
Comparator Nitroglycerin Unknown 10 mg Topical

Indications

No indication recorded.