drugset
drugset / Trial / NCT06303037

Effect of Esketamine on 95% Induction Dose of Remimazolam

NCT06303037 ↗

Phase 4 Completed 80 enrolled Second Affiliated Hospital of Wenzhou Medical University
RandomizedParallel-groupTriple-blindTreatment

Summary

As an invasive operation, gastroscopy will cause children's nervousness, anxiety and uncooperative behavior, and even lead to the risk of bleeding and perforation, which will also affect the accuracy of the examination results.The purpose of this study is to explore the influence of different doses of esketamine on the induced dose ED95 of remazolam during gastroscopic placement in children, and to provide theoretical basis for the combined use of remimazolam besylate and esketamine in gastroscopic anesthesia in children.

Timeline

Start
2024-04-01
Primary completion
2024-08-29
Completion
2024-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Esketamine Other / unclassified 0.25 mg/kg Intravenous
Subject Esketamine Other / unclassified 0.5 mg/kg Intravenous
Subject Remimazolam Small molecule 0.05 mg/kg Intravenous
Subject Remimazolam Small molecule 0.2 mg/kg Intravenous
Subject Remimazolam Small molecule 0.3 mg/kg Intravenous

Indications

No indication recorded.