drugset / Trial / NCT06304779
The Effect of Continuous Intravenous Infusion of Lidocaine on PPCs and Prognosis in Emergency Surgical Patients With IAI
Recruiting
428 enrolled
Shanghai Zhongshan Hospital
The Affiliated Hospital of Xuzhou Medical University · collabWest China Hospital · collab
RandomizedParallel-groupDouble-blindPrevention
Summary
The main purpose of this study is to evaluate the impact of continuous 24-hour intravenous infusion of lidocaine on the incidence of PPCs in patients undergoing emergency laparotomy for intra-abdominal infection (IAI).The secondary objectives of this study are to assess the impact of continuous 24-hour intravenous lidocaine infusion on the proportion of patients requiring mechanical ventilation, protection of important organ function during the perioperative period, length of hospital stay, and outcomes within 30 days postoperatively.
Timeline
- Start
- 2023-10-31
- Primary completion
- 2027-09-30
- Completion
- 2027-11-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lidocaine | Other / unclassified | 1.5 mg/kg | Intravenous |