drugset / Trial / NCT06305546
Comparisons Of Different Antiplaque Agents On Gingivitis In Orthodontic Patients
RandomizedParallel-groupTriple-blindPrevention
Summary
Fixed orthodontic treatment affects the periodontium by allowing plaque accumulation on teeth if the oral ecosystem is unfavorable which initially causes gingivitis to progress into periodontitis, and later enamel demineralization occurs. Yáñez-Vico et al observed that regular modifications per checkups were painful and unpleasant for the patient thus the patients undergoing fixed orthodontic treatments compromised their oral hygiene. This creates plaque retention sites which can lead to developing white spot lesions, caries, and periodontitis
Timeline
- Start
- 2023-04-01
- Primary completion
- 2023-10-31
- Completion
- 2023-10-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Chlorhexidine gluconate | Other / unclassified | 0.25 % | Topical |
| Subject | Metronidazole | Small molecule | 1 % | Topical |