drugset / Trial / NCT06305546

Comparisons Of Different Antiplaque Agents On Gingivitis In Orthodontic Patients

NCT06305546

Completed 80 enrolled Anam Sattar
RandomizedParallel-groupTriple-blindPrevention

Summary

Fixed orthodontic treatment affects the periodontium by allowing plaque accumulation on teeth if the oral ecosystem is unfavorable which initially causes gingivitis to progress into periodontitis, and later enamel demineralization occurs. Yáñez-Vico et al observed that regular modifications per checkups were painful and unpleasant for the patient thus the patients undergoing fixed orthodontic treatments compromised their oral hygiene. This creates plaque retention sites which can lead to developing white spot lesions, caries, and periodontitis

Timeline

Start
2023-04-01
Primary completion
2023-10-31
Completion
2023-10-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Chlorhexidine gluconate Other / unclassified 0.25 % Topical
Subject Metronidazole Small molecule 1 % Topical

Indications