drugset / Trial / NCT06312254
Pharmacological Modulation of Peripheral Nerve Excitability
RandomizedSingle-groupDouble-blindBasic science
Summary
The present project is a human experimental study. The aim is to assess the pharmacologically modulated excitability of peripheral sensory nerves with a human experimental model. The study measures the excitability of peripheral sensory nerves before and after application of different topical drugs (lidocaine (5%), phenytoin (10%),mepyramine (2%) and placebo).
Timeline
- Start
- 2024-04-09
- Primary completion
- 2024-12-02
- Completion
- 2024-12-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Lidocaine | Other / unclassified | 5 % | Topical |
| Comparator | PYRILAMINE | Small molecule | 2 % | Topical |
| Comparator | Phenytoin | Unknown | 10 % | Topical |