Hydroxychloroquine in Type 2 Diabetes During Pregnancy

Summary

The goal of this clinical trial is to compare the use of hydroxychloroquine as an adjunct to the current treatment of pregnant women with Type 2 diabetes mellitus. The main questions it aims to answer are: * Does hydroxychloroquine improve the pregnancy outcomes in women with type 2 diabetes during pregnancy? * Does hydroxychloroquine improve the inflammatory markers in women with type 2 diabetes during pregnancy? Participants will be randomised into the intervention and control group. The control group will be on standard treatment where as the intervention group will receive hydroxychloroquine as an adjunct of standard treatment

Timeline

Start

2024-03-24

Primary completion

2026-06-01

Completion

2027-01-01

Publications

• Basri NI, A Wahab N, Mohammed Nawi A, Ishak S, Murthi P, Abd Rahman R. Hydroxychloroquine as an adjunct therapy in the management of type 2 diabetes in pregnancy: study protocol for a randomised controlled trial. BMJ Open. 2026 Jan 20;16(1):e106653. doi: 10.1136/bmjopen-2025-106653.

Drugs

Indications