The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degeneration

Summary

Oral disulfiram (Antabuse®) has been shown to improve image-forming vision in animal models with retinal degeneration due to its ability to decrease Retinoic Acid synthesis and consequently reduce hyperactivity in the inner retina. The investigator will aim to evaluate the impact of oral disulfiram on the vision of patients with retinal degeneration who are being treated with the drug in the management of their concurrent alcohol use disorder.

Timeline

Start

2025-05-19

Primary completion

2029-05-19

Completion

2029-05-19

Drugs

Indications