drugset / Trial / NCT06330519

Enhancing Anaesthetic Success in Mandibular Molars With Symptomatic Irreversible Pulpitis: A Comparative Randomized Controlled Trial

NCT06330519 ↗

Phase 4 Completed 188 enrolled Ain Shams University
RandomizedParallel-groupSingle-blindSupportive care

Summary

The goal of this clinical trial is to assess the effect of * Preoperative intraligamentary corticosteroids injection * Cryotherapy which is cold application on : * Hard tooth structure ( crown of the tooth ) * Soft tissue overlying roots on the efficacy of the inferior alveolar nerve block anaesthesia in patients with mandibular molars with symptomatic irreversible pulpitis. The main question it aims to answer are: • Does intraligamentary dexamethazone injection increase the success rate of inferior alveolar nerve block without the need for oral premedication. Participants will describe their preoperative pain level to the investigator and describe their pain level during the treatment. Researchers will compare cryotherapy to see if it increases the success rate of inferior alveolar nerve block.

Timeline

Start
2023-02-01
Primary completion
2024-03-01
Completion
2024-03-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexamethasone Small molecule 0.8 ml Other

Indications