drugset / Trial / NCT06332157
Postoperative Quality of Recovery After General Anesthesia With Remimazolam
RandomizedParallel-groupDouble-blindTreatment
Summary
126 patients undergoing general anesthesia for elective surgery in Beijing Chaoyang Hospital were selected. In the intervention group, anesthesia was induced with remimazolam besylate at a rate of 6mg/min; Anesthesia was maintained with 1.0-2.0mg/min remimazolam besylate by continuous pump. Control group: anesthesia induction, intravenous injection of propofol 2mg/kg; Anesthesia was maintained by continuous pumping of 6-8mg/kg/h propofol. All patients were routinely monitored for vital signs and anesthesia depth after entering the operating room. The patients were followed up after surgery, and the quality of recovery score at 24 hours after surgery was the main study outcome.
Timeline
- Start
- 2024-09
- Primary completion
- 2025-12
- Completion
- 2025-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Propofol | Small molecule | 6 mg/kg | Intravenous |
| Comparator | Propofol | Small molecule | 8 mg/kg | Intravenous |
| Subject | Remimazolam | Small molecule | 1 mg | — |
| Subject | Remimazolam | Small molecule | 2 mg | — |
Indications
No indication recorded.