drugset / Trial / NCT06339281

A Multicenter Clinical Study of Apatinib Mesylate Combined With Doctor's Choice for Advanced Breast Cancer

NCT06339281

Phase 2 Not yet recruiting 68 enrolled Li Huiping
RandomizedParallel-groupOpen-labelTreatment

Summary

Previous studies have found good efficacy of (investigator's choice of chemotherapy, or endocrine drug) in combination with apatinib mesylate in the treatment of her-2 negative, chest wall metastatic advanced breast cancer, and the present study proposes to further explore the efficacy of apatinib mesylate in her-2 negative, HR-positive advanced breast cancer.

Timeline

Start
2024-05-01
Primary completion
2026-06
Completion
2026-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Capecitabine Small molecule 1000 mg/m2 Oral
Comparator Fulvestrant Small molecule 500 mg Intramuscular
Comparator Rivoceranib Small molecule 500 mg Oral

Indications