Sequential Vaccination of Poliomyelitis Vaccine (Vero Cells), Inactivated, Sabin Strains From Different Manufacturers

Summary

To evaluate the immunogenicity and safety of sequential vaccination with Sinovac sIPV among infants who have received two doses of Biological Products Co., Ltd. sIPV.

Timeline

Start

2024-05-20

Primary completion

2024-09-06

Completion

2024-12-06

Outcome

Met primary endpoint

release “这项由湖北省疾控中心牵头开展的研究结果显示，在婴幼儿已完成两剂其他厂家Sabin株脊髓灰质炎灭活疫苗(sIPV)的基础上，第三剂序贯接种科兴sIPV，不仅能诱导相对更优的免疫应答，同时表现出良好的安全性。” sinovac.com ↗

release “序贯接种三型脊灰抗体阳转率均相对高于同源接种对照组 ，Ⅱ型差异具有统计学意义(67.47% vs. 49.43%，p = 0.017)” sinovac.com ↗

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	sIPV	Vaccine	—	—

Indications