drugset / Trial / NCT06354387

Alectinib in Combination With Nivolumab in the Treatment of Recurrent or Refractory HCC Patients Guided With Serum RNase1 and Tumor Expression of PD-L1

NCT06354387

Phase 1 Completed 5 enrolled China Medical University Hospital
NaSingle-groupOpen-labelTreatment

Summary

Hepatocellular carcinoma (HCC) is the fourth most common cause of cancer-related death and the second most deadly malignancy in Taiwan. Despite decades' intensive studies, surgery and local-regional chemo-embolization, radio-frequency ablation or radiation therapy remain the mainstay of HCC treatments.

Timeline

Start
2022-02-16
Primary completion
2026-02-28
Completion
2026-02-28

Drugs

EvaluationDrugModalityDoseRoute
Subject Alectinib Small molecule
Subject Nivolumab Monoclonal antibody