Effects of Different Inhaled Oxygen Concentrations on Lung Function in Older Patients After Laparoscopic Gastrointestinal Surgery Under General Anesthesia

Phase 4 Recruiting 1176 enrolled China Medical University, China

RandomizedParallel-groupTriple-blindTreatment

Summary

This was a multicenter, prospective, parallel-grouping, randomized controlled clinical study comparing low FiO2 (40%) and high FiO2 (80%) levels in older patients undergoing laparoscopic gastrointestinal surgery.

Timeline

Start: 2024-07-02
Primary completion: 2026-06-30
Completion: 2026-06-30

Publications

Zhang T, An Y, Zhao S, Han F, Huang L, Wang L, Wu J, Lei Q, Wang K, Shao J, Wang Y, Luan Y, Feng W, Song J, Huang Z, Wu C, Nan Y, Tang B, Sun X, Tan W. Effects of varying inhaled oxygen concentrations on lung function in older adult patients undergoing laparoscopic gastrointestinal surgery under general anesthesia: protocol of a prospective multicenter clinical study in China. Trials. 2026 Jan 23;27(1):139. doi: 10.1186/s13063-026-09471-3.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Oxygen	Other / unclassified	40 %	Inhaled
Subject	Oxygen	Other / unclassified	80 %	Inhaled

Indications

No indication recorded.