drugset / Trial / NCT06367374
MRD Guided Sonrotoclax and Zanubrutinib in Newly Diagnosed CLL/SLL
NaSingle-groupOpen-labelTreatment
Summary
This is a single-arm, open-label study of sonrotoclax plus zanubrutinib with MRD-driven treatment duration in patients with previously untreated Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL). The primary goal of this study is to evaluate the efficacy of MRD-guided zanubrutinib plus sonrotoclax for first-line CLL/SLL treatment.
Timeline
- Start
- 2024-05-30
- Primary completion
- 2030-02-28
- Completion
- 2030-07-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Sonrotoclax | Other / unclassified | 320 mg | — |
| Subject | Zanubrutinib | Small molecule | 160 mg | Oral |