drugset / Trial / NCT06369077
How Much Does Reduced Dosing of Latanoprost and Dorzolamide-timolol Affect Pressure?
RandomizedCrossoverSingle-blindTreatment
Summary
IOP effect of half-dose latanoprost dorzolamide-timolol will be compared to full dose. Further comparison will be made timolol-brimonidine-dorzolamide-bimatoprost. Dry eye effects of the different treatments will be assessed.
Timeline
- Start
- 2024-04-22
- Primary completion
- 2024-07-30
- Completion
- 2024-07-30
Outcome
Outcome not reported
Stopped (Enrollment): “The 95% confidence interval for non-inferiority was met before planned enrollment was reached.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Bimatoprost | Other / unclassified | — | — |
| Comparator | Brimonidine | Unknown | — | — |
| Comparator | Dorzolamide | Small molecule | — | — |
| Comparator | Latanoprost | Small molecule | — | — |
| Comparator | Timolol | Other / unclassified | — | — |