drugset / Trial / NCT06377111
A Study to Test the Benefit of Vitamin B5 in Patients With Melanoma
NaSingle-groupOpen-labelTreatment
Summary
This study is open to patients with a type of cancer called melanoma. Patients can join the study if their tumor cannot be removed by surgery or has spread to other organs, and are planned to receive immunotherapy as treatment for their cancer. This study is looking at whether taking calcium pantothenate supplement (a type of Vitamin B5) can increase its levels in the blood and have an effect in the immune system, when its used in combination with the immunotherapy.
Timeline
- Start
- 2024-06-24
- Primary completion
- 2027-08
- Completion
- 2027-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Ipilimumab | Monoclonal antibody | 3 mg/kg | — |
| Background | Nivolumab | Monoclonal antibody | 3 mg/kg | — |
| Background | Nivolumab | Monoclonal antibody | 6 mg/kg | — |
| Background | Nivolumab | Monoclonal antibody | 240 mg | — |
| Background | Nivolumab | Monoclonal antibody | 480 mg | — |