drugset / Trial / NCT06382467
Comparison of Remimazolam and Propofol Combination vs. Propofol in IOM
RandomizedParallel-groupDouble-blindTreatment
Summary
This study aims to compare total intravenous anesthetic agents: combined remimazolam and propofol vs. propofol monotherapy. The comparison parameters are intraoperative hypotension, patient's involuntary movement, neurophysiological monitoring quality, onset time, recovery time, and postoperative rescue anti-emetics requirements.
Timeline
- Start
- 2024-05
- Primary completion
- 2025-05
- Completion
- 2025-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Propofol | Small molecule | 1 ug/ml | Intravenous |
| Comparator | Propofol | Small molecule | 2 ug/ml | Intravenous |
| Comparator | Propofol | Small molecule | 4 ug/ml | Intravenous |
| Comparator | Propofol | Small molecule | 8 ug/ml | Intravenous |
| Subject | Remimazolam | Small molecule | 0.5 mg/kg | Intravenous |